Erik ten Hag makes six changes to the team that beat Chelsea. In come Diogo Dalot, Harry Maguire, Tyrell Malacia, Fred, Marcus Rashford and Alejandro Garnacho.
Just the one change to the Fulham team as Marco Silva brings in Sasa Lukic into his midfield. Harrison Reed drops to the bench.
Man Utd team news
Team to play Fulham: De Gea, Dalot, Lindelof, Maguire, Malacia, Casemiro, Fred, Sancho, Fernandes, Garnacho, Rashford.
Subs: Butland, Martial, Eriksen, Varane, Shaw, Weghorst, Pellistri, Wan-Bissaka, McTominay.
Fulham team news
Team to play Man Utd: Leno, Tete, Adarabioyo, Diop, Robinson, Palhinha, Lukic, Cairney, Wilson, Mitrovic, Willian.
Subs: Rodak, Reed, Kebano, Solomon, Soares, De Cordova-Reid, James, Vinicius, Dibley-Dias.