Ghana have made two changes from their 3-2 win against South Korea.
Alidu Seidu and Baba Rahman come into the XI with Tariq Lamptey and Gideon Mensah dropping to the bench.
Uruguay make three changes – with Ghana’s old nemesis, Luis Suarez, back in the starting XI.
Giorgian de Arrascaeta and Facundo Pellistri round of the players back in the XI, with captain Diego Godin, Matias Vecino and Edinson Cavani dropping to the bench.
Uruguay team news
Uruguay XI: Rochet, Varela, Gimenez, Coates, Olivera, Pellistri, Valverde, Bentancur, De Arrascaeta, Suarez, Nunez.
Subs: Muslera, Godin, Vecino, De la Cruz, Sosa, Torreira, Vina, Gomez, Torres, Cavani, Caceres, Canobbio, Ugarte, Luis Rodriguez.
Ghana team news
Ghana XI: Ati-Zigi, Seidu, Amartey, Salisu, Baba Rahman, Partey, Abdul Samed, Kudus, Andre Ayew, Jordan Ayew, Williams.
Subs: Lamptey, Odoi, Owusu, Fatawu, Kyereh, Bukari, Danlad, Afriyie, Mensah, Aidoo, Nurudeen, Sulemana, Djiku, Sowah, Semenyo.