Emi Martinez starts for Aston Villa despite coming off with a head injury in their last game against Newcastle.
The only change in Unai Emery’s first game in charge is Jacob Ramsey coming into the first XI, replacing Ashley Young.
Aston Villa XI: Martinez, Cash, Konsa, Mings, Digne, Dendoncker, Douglas Luiz, Ramsey, Buendia, Bailey, Watkins.
Subs: McGinn, Sanson, Ings, Chambers, Augustinsson, Young, Bednarek, Olsen, Kamara.
Cristiano Ronaldo starts and captains the Manchester United side.
The only change from the midweek win at Real Sociedad sees Marcus Rashford in for the suspended Bruno Fernandes, meaning Donny Van de Beek makes a rare Premier League start – it is his first for United since the 2020-21 season.
Man Utd XI: de Gea, Dalot, Lindelof, Martinez, Shaw, Casemiro, Eriksen, Rashford, van de Beek, Garnacho, Ronaldo.
Subs: Maguire, Martial, Malacia, Fred, Pellistri, Dubravka, Elanga, McTominay, Shoretire.