As expected David Raya, who couldn’t play for Arsenal against parent club Brentford at the weekend, returns in goal, with Aaron Ramsdale among the substitutes in the only change from their last match.
Gabriel Martinelli is not in the squad with a foot injury.
Arsenal XI: Raya, White, Saliba, Kiwior, Gabriel, Rice, Jorginho, Odegaard, Saka, Trossard, Havertz.
Subs: Ramsdale, Hein, Tomiyasu, Soares, Zinchenko, Elneny, Partey, Vieira, Smith Rowe, Nelson, Nketiah, Jesus.
Porto are third in the Primeira Liga and their side includes two players called Pepe – the veteran Portuguese defender and the Brazilian winger.
Galeno has scored five times in this season’s Champions League and also registered three assists.
Porto XI: Costa, Mario, Pepe, Otavio, Wendell, Varela, Nico, Pepe, Conceicao, Evanilson, Galeno.
Subs: Ramos, Pedro, Cardoso, Sanchez, Grujic, Eustaquio, Jaime, Baro, Borges, Taremi, Namaso, Martínez.