Just the one change for Mikel Arteta and it is an expected one with Oleksandr Zinchenko unavailable due to injury. He is replaced by Kieran Tierney.
Four changes to the Brighton team that were badly beaten at home to Everton. One is enforced as the injured Adam Webster is replaced by Levi Colwill.
Also in are Julio Enciso, Billy Gilmour and Evan Ferguson. Out go Deniz Undav, Danny Welbeck and Facundo Buonanotte.
Arsenal team news
Arsenal team to play Brighton: Ramsdale, White, Kiwior, Gabriel, Tierney, Jorginho, Xhaka, Saka, Odegaard, Martinelli, Jesus.
Subs: Turner, Partey, Smith Rowe, Nketiah, Holding, Trossard, Vieira, Nelson, Walters.
Brighton team news
Brighton team to play Arsenal: Steele, Gross, Dunk, Colwill, Estupinan, Gilmour, Caicedo, Mac Allister, Enciso, Ferguson, Mitoma.
Subs: McGill, Welbeck, Undav, Ayari, Van Hecke, Buonanotte, Offiah, Moran, Peupion.