Luis Enrique returns to his strongest possible Paris St-Germain side, making 10 changes from the team that drew 1-1 with Clermont in Ligue 1 on Saturday.
Spain midfielder Marco Asensio is the only player to keep his place, while winger Kylian Mbappe, goalkeeper Gianluigi Donnarumma and captain Marquinhos come back in.
PSG XI: Donnarumma, Hernandez, Marquinhos, Lucas Beraldo, Nuno Mendes, Lee, Vitinha, Fabian Ruiz, Dembele, Mbappe, Asensio.
Subs: Navas, Tenas, Ugarte, Ramos, Danilo, Kolo Muani, Soler, Barcola, Zaire-Emery, Skriniar, Mayulu, Zague.
PSG XI to play Barcelona: Donnarumma, Hernandez, Marquinhos, Lucas Beraldo, Nuno Mendes, Lee, Vitinha, Fabian Ruiz, Dembele, Mbappe, Asensio.
Barcelona have had 11 days off in the build-up to his one and boss Xavi makes two changes from the 1-0 win over Las Palmas.
Ronald Araujo comes in at the back and partners 17-year-old Pau Cubarsi, who becomes the youngest defender to start a Champions League quarter-final.
The other switch sees Frenkie de Jong replace Fermin Lopez in midfield.
There’s also a start for 16-year-old winger Lamine Yamal.
Barcelona XI: Ter Stegen, Kounde, Araujo, Cubarsi, Cancelo, Roberto, De Jong, Gundogan, Yamal, Lewandowski, Raphinha.
Subs: Martínez, Torres, Pedri, Pena, Felix, Christensen, Alonso, Romeu, Roque, Astralaga, Lopez, Fort.