There are four changes to the Tottenham side from their victory over Bournemouth in the Premier League.
Davinson Sanchez drops to the bench alongside Emerson Royal, Yves Bissouma and Oliver Skipp.
Returning to the side are Ivan Perisic, Ben Davies, Rodrigo Bentancur and Lucas Moura.
Tottenham XI: Lloris, Perisic, Dier, Lenglet, Davies, Sessegnon, Bentancur, Hojbjerg, Lucas, Son, Kane.
Subs: Forster, Royal, Spence, Doherty, Sanchez, Tanganga, Skipp, White, Bissouma, Sarr, Bryan.
There’s a lot of ex-Arsenal representation in the Marseille squad.
Former Gunners and Manchester United striker Alexis Sanchez starts alongside Nunes Tavares, currently on loan from Arsenal.
Former Arsenal full-back Sead Kolasinac is on the bench, alongside ex-West Ham midfielder Dimitri Payet.
Marseille XI: Pau Lopez, Mbemba, Bailly, Balerdi, Rongier, Veretout, Clauss, Guendouzi, Harit, Tavares, Sanchez.
Subs: Ngapandouentnbu, Blanco, Gigot, Gerson, Payet, Suarez, Under, Kolasinac, Kaboure.
Conte blames VAR
Conte has claimed VAR caused “damage” after they were denied a late winner against Sporting Lisbon in the Champions League.
Harry Kane swept home Emerson Royal’s knockdown in the late minute of injury-time.
But the goal was ruled out for offside after a three-minute VAR check, with manager Conte shown a red card in the ensuing chaos.
VAR adjudged Kane to be in an offside position when Royal headed down a cross but the pundits analysing the match – and the majority of fans – thought the England striker was behind play and therefore could not be flagged.
Conte said: “I think the ball was in front of Kane and the goal is a goal. Yeah. I don’t understand the line they put. It very difficult to comment on this decision.
“VAR is doing a lot of damage. I want to see if in another stadium of a big team if they are ready to disallow this type of goal. I’d like to know this.
“A lot of injustice. I don’t like this type of situation. Because I see not positive things.
“I don’t understand why we have to get something from the next game when we can finish the qualification in this game. When you invent this type of situation, you create a lot of damage of the club. Also problems.
“The second half was positive and we played with a great intensity. We deserved to win but we know what happened.”