Manchester United begin their European campaign looking to make it five consecutive wins in all competitions under Erik ten Hag.
Real Sociedad are hoping to stretch their unbeaten run to three matches.
Kick-off is at 8pm and here is the official team news:
Man Utd team to play Real Sociedad: De Gea, Dalot, Lindelof, Maguire, Malacia, Fred, Casemiro, Eriksen, Antony, Elanga, Ronaldo.
Man Utd subs: Dubravka, Heaton, Fredericson, Martinez, Varane, Wan-Bissaka, Fernandes, Iqbal, McTominay, Sancho, Garnacho, McNeill.
Real Sociedad team to play Man Utd: Remiro, Gorosabel, Elustondo, Pacheco, Munoz, Zubimendi, Mendez, Merino, Silva, Kubo, Sadiq.
Real Sociedad subs: Sola, Illarramendi, Zubeldia, Barrenetxea, Cho, Zubiaurre, Guevara, Navarro, Sorloth, Turrientes, De Zarate, Karrikaburu.
Referee: Marco Di Bello.