Darwin Nunez has been rewarded for his substitute heroics at Newcastle last weekend with a first start of the season.
The Uruguayan, who scored two late goals against Eddie Howe’s side, replaces Coady Gakpo up front with the Dutchman dropping to the bench.
Curtis Jones is also handed a first start of the campaign with the midfielder returning from an ankle injury to come in for Wataru Endo.
The third and final change from the 2-1 win at Newcastle is an enforced one with Joe Gomez taking the place of the suspended Virgil van Dijk following his red card at St James’ Park.
With Van Dijk absent, Trent Alexander-Arnold captains the side.
Liverpool team news: Nunez & Jones start
Team to play Aston Villa: Alisson, Robertson, Gomez, Matip, Alexander-Arnold, Jones, Mac Allister, Szoboszlai, Nunez, Salah, Diaz
Subs: Kelleher, Endo, Gakpo, Elliott, Tsimikas, Doak, Bajcetic, Jota, Quansah
Aston Villa team news – Martinez returns
Team to play Liverpool: Martinez, Konsa, Carlos, Torres, Cash, Kamara, Luiz, Digne, Diaby, McGinn, Watkins
Subs: Olsen, Lenglet, Tielemans, Chambers, Zaniolo, Duran, Bailey, Dendoncker, Kellyman