Manchester City make four changes to the starting line-up which lost to Wolves.
Bernardo Silva is back from injury and Rodri is not suspended in Europe so they come in, alongside ex-Leipzig defender Josko Gvardiol and Jack Grealish.
Nathan Ake, Matheus Nunes, Jeremy Doku and Julian Alvarez drop to the bench.
John Stones, who hasn’t played since the Community Shield because of injury, is named among the subs.
Man City XI: Ederson, Walker, Akanji, Dias, Gvardiol, Lewis, Rodri, Bernardo, Foden, Grealish, Haaland.
Subs: Moreno, Carson, Phillips, Stones, Ake, Kovacic, Doku, Alvarez, Gomez, Nunes, Bobb.
Leipzig make two changes from their draw against Bayern Munich.
Nicolas Seiwald and Lukas Klostermann replace Kevin Kampl and Benjamin Henrichs. Timo Werner is on the bench.
Leipzig XI: Blaswich, Klostermann, Simakan, Castello, Raum, Simons, Seiwald, Schlager, Forsberg, Openda, Poulsen.
Subs: Gulacsi, Lenz, Haidara, Werner, Baumgartner, Carvalho, Sesko, Kampl.