Mauricio Pochettino makes three changes to the side that drew 2-2 at home to Arsenal last time out.
Axel Disasi returns from injury in place of Malo Gusto, which may see Marc Cucurella shift to right-back.
Noni Madueke and Nicolas Jackson also return to the side in place of Mykhailo Mudryk – who is not in the squad – and Enzo Fernandez, whose partner gave birth this week.
Robert Sanchez retains his place in goal despite another shaky display against Arsenal, including making the error that handed Declan Rice the Gunners’ first goal and sparked their comeback.
Chelsea team news
Team to play Brentford: Sanchez, Cucurella, Silva, Disasi, Colwill, Caicedo, Palmer, Gallagher, Sterling, Jackson, Madueke.
Subs: Beach, Badiashile, Ugochukwu, James, Gusto, Petrovic, Maatsen, Washington, Matos.
Brentford team news
Team to play Chelsea: Flekken, Hickey, Ajer, Pinnock, Collins, Janelt, Jensen, Roerslev, Norgaard, Wissa, Mbeumo.
Subs: Strakhosha, Maupay, Zanka, Ghoddos, Onyeka, Mee, Yarmolyuk, Olakigbe, Brierley.