There are two changes to the Real Madrid side that were held to a 1-1 draw by Osasuna at the weekend.
Eder Militao returns to partner David Alaba in defence with Antonio Rudiger dropping to the bench, while Federico Valverde is preferred to Dani Ceballos in midfield.
Real Madrid XI: Lunin, Carvajal, Militao, Alaba, Mendy, Valverde, Kroos, Tchouameni, Rodrygo, Vinicius, Benzema.
There is just one change to the Shakhtar Donetsk side that thrashed Metalist Kharkiv 6-1 on Saturday, with Danylo Sikan – who scored a hat-trick in that game – making way for Maryan Shved.
Shakhtar Donetsk XI: Trubin, Konoplia, Bondar, Matviyenko, Mykhaylichenko, Stepanenko, Zubkov, Bondarenko, Sudakov, Mudryk, Shved.