Manchester United make two changes to the side that lost 4-3 to Chelsea deep into stoppage time.
Teenager Willy Kambwala makes just his second league start for the Red Devils, coming in for the injured Raphael Varane. Jonny Evans, who replaced Varane in that game, is also injured.
Marcus Rashford is preferred to Antony.
Full-backs Harry Amass, 17 and Habeeb Ogunneye, 18, are the only two defenders on the United bench.
Manchester United XI: Onana; Wan-Bissaka, Maguire, Kambwala, Dalot; Casemiro, Mainoo; Garnacho, Fernandes, Rashford; Hojlund.
Subs: Bayindir, Amrabat, Mount, Eriksen, Diallo, Antony, Forson, Amass, Ogunneye.
As for Liverpool, they make three changes to the team that beat Sheffield United 3-1 on Thursday night.
Jarell Quansah, Andy Robertson and Wataru Endo all come in.
Joe Gomez, Ibrahima Konate and Ryan Gravenberch drop to the bench.
Liverpool XI: Kelleher; Bradley, Quansah, Van Dijk, Robertson; Mac Allister, Endo, Szoboszlai; Salah, Nunez, Diaz.
Subs: Adrián, Gomez, Konaté, Jones, Gakpo, Elliott, Tsimikas, Gravenberch, Danns.