Manchester United manager Erik ten Hag has made three changes from the side that beat Brentford 1-0 on Wednesday.
Tyrell Malacia replaces the injured Luke Shaw at left-back, while Aaron Wan-Bissaka comes in for right-back Diogo Dalot and captain Harry Maguire replaces Raphael Varane at centre-back.
Christian Eriksen returns for United. He’s among the substitutes.
Everton boss Sean Dyche has made one change following Monday’s 1-1 draw with Tottenham.
Striker Ellis Simms replaces the suspended Abdoulaye Doucoure. Dominic Calvert-Lewin is not fit to make the matchday squad.
Everton team news
Everton starting XI: Pickford, Coleman, Tarkowski, Keane, Godfrey, Onana, Gueye, Iwobi, McNeil, Gray, Simms.
Subs: Begovic, Patterson, Holgate, Mina, Mykolenko, Maupay, Davies, Coady, Garner.
Man Utd team news
Man Utd starting XI: De Gea, Wan-Bissaka, Maguire, Martinez, Malacia, McTominay, Sabitzer, Antony, Fernandes, Sancho, Rashford.
Subs: Butland, Lindelof, Martial, Eriksen, Fred, Varane, Dalot, Weghorst, Pellistri.