Manchester City boss Pep Guardiola makes three changes from the side who beat Nottingham Forest 2-0 last Sunday.
Phil Foden returns to the line up after missing the last match through illness and Erling Haaland is also back in the side from the start.
Mateo Kovacic replaces Jack Grealish in City’s other change.
Manchester City XI: Ederson, Gvardiol, Ake, Akanji, Walker, Rodri, Kovacic, Silva, De Bruyne, Foden, Haaland.
Subs: Ortega, Dias, Stones, Grealish, Doku, Alvarez, Gomez, Nunes, Lewis.
Wolves head coach Gary O’Neil serves a one-match touchline ban following his reaction to a disallowed goal against West Ham last month.
He makes just one change to the side who beat Luton 2-1 last Saturday as Hugo Bueno comes in for Matt Doherty in defence.
Jean-Ricner Bellegarde and Santiago Bueno are on the bench after resuming training.
Wolves XI: Sa, Semedo, Kilman, Gomes, H Bueno, Gomes, Lemina, Traore, Ait-Nouri, Cunha, Hwang.
Subs: Bentley, Doherty, S Bueno, Sarabia, Bellegarde, Gonzalez, Okoduwa, Chirewa, Fraser.