Leeds make just one change to the side that lost 1-0 at Crystal Palace last time out.
Luis Sinisterra returns from his one game suspension and replaces Patrick Bamford up top.
Leeds XI: Meslier, Kristensen, Koch, Cooper, Struijk, Adams, Roca, Aaronson, Rodrigo, Harrison, Sinisterra.
Arsenal make seven changes to the side that beat Bodo/Glimt in the Europa League during the week.
The big hitters including Gabriel Jesus, Gabriel Martinelli, Gabriel, Granit Xhaka, Thomas Partey, Takehiro Tomiyasu and Aaron Ramsdale all return to the starting line-up.
Eddie Nketiah, Reiss Nelson, Rob Holding, Albert Sambi Lokonga, Fabio Vieira, Kieran Tierney and Matt Turner all drop out.
Arsenal XI: Ramsdale, White, Saliba, Gabriel, Tomiyasu, Xhaka, Partey, Saka, Odegaard, Martinelli, Jesus.