Defenders Michael Keane, with whom Sean Dyche worked at Burnley, and Ben Godfrey are edging closer to fitness from knee injuries but midfielder James Garner is still some time away from recovering from a back problem.
Emile Smith Rowe has been ruled out of the game but Thomas Partey could be fit despite having an MRI scan after picking up an injury in the FA Cup defeat at Manchester City.
Deadline-day signing Jorginho could also feature having joined from Chelsea as Mikel Arteta finally landed a player he has long admired.
Everton team news
Team to face Arsenal: Pickford, Coleman, Coady, Tarkowski, Mykolenko, McNeil, Doucoure, Gana, Onana, Iwobi, Calvert-Lewin.
Subs: Begovic, Holgate, Gray, Mina, Maupay, Godfrey, Davies, Vinagre, Simms.
Arsenal team news
Team to face Everton: Ramsdale, White, Saliba, Gabriel, Zinchenko, Thomas, Odegaard, Xhaka, Saka, Nketiah, Martinelli.
Subs: Turner, Tierney,Kiwior, holding, Tomiyasu, Trossard, Jorginho, Vieira, Cozier-Duberry.