Dortmund’s starting line-up features two changes from the first leg, with injured goalscorer Kevin Adeyemi replaced by Marco Reus and Alexander Meyer starting in goal in place of Gregor Kobel.
Jude Bellingham starts in midfield, as expected, while Jamie Bynoe-Gittens, another Englishman, is among the substitutes.
The big news from the Chelsea line-up is that Reece James is fit to start having missed the 1-0 win over Leeds at the weekend.
That’s a major boost for Graham Potter and his inclusion at the expense of Ruben Loftus-Cheek is one of two changes, with Marc Cucurella also returning for a first start since the 1-1 draw with West Ham on February 11, with Benoit Badiashile dropping out.
Remember, Badiashile, like Pierre-Emerick Aubameyang is not in Chelsea’s Champions League squad and therefore unavailable.
It looks like Potter will persist with a back three following the much-needed win over Leeds.
Borussia Dortmund team news
Team to Chelsea: Meyer, Wolf, Süle, Schlotterbeck, Guerreiro, Emre Can, Salih Ozcan, Brandt, Bellingham, Reus, Haller
Subs: Kobel, Unbehaun, Reyna, Dahoud, Hummels, Modeste, Malen, Meunier, Passlack, Rothe, Bynoe-Gittens, Coulibaly
Chelsea team news – James, Cucurella start!
Team to Borussia Dortmund: Kepa, Cucurella, Koulibaly, Fofana, James, Chilwell, Kovacic, Fernandez, Sterling, Havertz, Felix
Subs: Bettinelli, Bergstrom, Pulisic, Loftus-Cheek, Chalobah, Mudryk, Zakaria, Ziyech, Gallagher, Hall, Chukwuemeka