Aston Villa have made three changes from the 2-2 draw against Chelsea on Saturday.
Emi Martinez drops out through suspension, replaced by Robin Olsen in goal.
Pau Torres is on the bench, making way for Clement Lenglet at centre-back.
Youri Tielemans is missing tonight through injury and Moussa Diaby has been brought in to the side as a result.
Daniel Podence starts for the Greek side this evening.
The 28-year-old forward is on loan at Olympiakos from Wolves.
Podence has 14 goals and 10 assists in all competitions this season.
Stefan Jovetic, the former Man City striker, is also on the bench, along with Nottingham Forest’s on-loan defender Omar Richards.
Olympiakos team news
Team to face Aston Villa: Tzolakis, Ortega, Chiquinho, Fortounis, Iborra, El Kaabi, David Carmo, Rodinei, Hezze, Restos, Podence.
Subs: Paschalakis, Papdoudis, Andre Horta, El-Arabi, Alexandropoulos, Quini, Joao Carvalho, Jovetic, Richards, Prekates.
Aston Villa team news
Team to face Olympiakos: Olsen; Cash, Konsa, Lenglet, Digne; Bailey, McGinn, Douglas Luiz, Rogers; Diaby, Watkins.
Subs: Gauci, Wright, Diego Carlos, Torres, Zaniolo, Duran, Iroegbunam, Kesler-Hayden, Munroe, Kellyman, Young.