Arsenal have made just one change from their 6-0 Champions League triumph over RC Lens in midweek.
Kai Havertz, who has two goals in two games, drops to the bench and Leandro Trossard starts.
It is the same outfield team that beat Brentford 1-0 last weekend, with David Raya returning in the Premier League after he was ineligible for the game against his parent club.
Arsenal team news
Team to play Wolves: Raya; Tomiyasu, Saliba, Gabriel, Zinchenko; Rice, Odegaard, Trossard; Saka, Jesus, Martinelli
Substitutes: Ramsdale, White, Nketiah, Kiwior, Cedric, Jorginho, Nelson, Elneny, Havertz
Wolves team news
Team to play Arsenal: Sa; Dawson, Kilman, Toti; Semedo, Traore, Doyle, Bellegarde, Bueno; Cunha, Hwang
Substitutes: Bentley, Doherty, Bueno, Silva, Kaladjzic, Sarabia, Chirewa, Whittingham, Hubner