Arsenal have made two changes to the side who beat Wolves 2-0 on Saturday.
Gabriel Jesus misses out with Thomas Partey coming in while Jakub Kiwior settles for a place on the bench as Takehiro Tomiyasu comes back in to the defence.
Arsenal starting XI: Raya, White, Saliba, Gabriel, Tomiyasu, Odegaard, Rice, Partey, Saka, Havertz, Trossard.
Subs: Ramsdale, Jesus, Smith Rowe, Martinelli, Nketiah, Kiwior, Jorginho, Vieira, Zinchenko.
Chelsea have made four changes to the side who were narrowly beaten 1-0 by Man City in the FA Cup semi-final on Saturday.
Malo Gusto, Trevoh Chalobah and Thiago Silva miss out in the defence as Axel Disasi, Benoit Badiashile and Alfie Gilchrist come in to the starting XI.
Bad news for Chelsea as top scorer Cole Palmer misses out with illness and Mykhailo Mudryk starts in his place.
Chelsea starting XI: Petrovic, Gilchrist, Badiashile, Disasi, Cucurella, Fernandez, Mudryk, Madueke, Caicedo, Gallagher, Jackson.
Subs: Bettinelli, Silva, Sterling, Chalobah, Chukwuemeka, Casadei, Deivid, Tauriainen, Dyer.