Arsenal boss Mikel Arteta has named an unchanged team from the 3-2 win over Tottenham on Sunday.
Thomas Partey keeps his place in midfield, Leandro Trossard gets the nod over Gabriel Martinelli on the left and the in-form Kai Havertz continues to lead the line.
Arteta said Jurrien Timber was available again following his injury ahead of the game but the Dutch international is not involved.
Illia Zabarnyi returns in defence as one of two changes for Bournemouth following their 3-0 win over Brighton, with Ryan Christie also coming back into the side.
Enes Unal drops to the bench while Lloyd Kelly is not in the squad.
Arsenal XI: Raya, White, Saliba, Gabriel, Tomiyasu, Partey, Odegaard, Rice, Saka, Havertz, Trossard.
Bournemouth XI: Travers, Smith, Senesi, Zabarnyi, Ouattara, Cook, Christie, Kluivert, Scott, Semenyo, Solanke.